MORF4L2 antibody (N-Term)

Catalog No. ABIN374201

The Goat Polyclonal anti-MORF4L2 antibody has been validated for WB. It is suitable to detect MORF4L2 in samples from Human and Dog.

Quick Overview for MORF4L2 antibody (N-Term) (ABIN374201)

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Reactivity: Human, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This MORF4L2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MORF4L2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects MORF4L2 at N-term.

Cross-Reactivity (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence SSRKQGSQPRGQQS-C, from the N Terminus of the protein sequence Genename: MORF4L2

Application Details

Application Notes: Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 35 kDa band observed in Human Brain and A431 lysates(calculated MW of 32.5 kDa according to NP_036418.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MORF4L2

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Alternative Name: MORF4L2

Background: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes mainly by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also be involved in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. May also interact with one or more as yet undefined members of the TLE (transducin like enhancer of split) family of transcriptional repressors.Synonyms: KIAA0026, MORF-related gene X protein, MORF4L2, MRGX, MSL3-2 protein, Mortality factor 4-like protein 2, Transcription factor-like protein MRGX

Gene ID: 9643

NCBI Accession: NP_036418

UniProt: Q15014

Pathways: Regulation of Muscle Cell Differentiation